Activator Enhancer Promoter Repressor Silencer Promoter Enhancer andSample Page silencer DNA elements regulate gene expression by serving as binding sites for regulatory trasncription factors. Transcription factors contain functionally separable domains that dictate their ability to bind “distal” regulatory elements like Enhancers or Silencers and recruit complexes that activate or represss transcription. To test the hypothesis eukaryotic transcription factors are modular you proceed to engineer chimeric proteins and also create genetic mutants. What would you expect to be the outcome of 1) combining the activation domain with the DNA-binding domain specific for Silencer DNA elements, or 2) adding mutiple copies of Enhancer DNA sequences to the Repressor (illustrated above) when you measure gene expression by qPCR? An increase in transcription of the target gene. An increase in transcription of the Silencer DNA region. A decrease in transcription. O No transcription of the target gene.