Operations

191 views 8:26 am 0 Comments July 25, 2023

C-terminal His-tagged Calcitonin (5 grams) and untagged GLP-1 peptide (10 grams) are accidentally mixed in 1L of 0.5M imidazole buffer.Marketing Research and Data Analysis QC confirmed that there are no other impurities in the mixture. Design a suitable downstream purification scheme to obtain pharmaceutical-grade calcitonin and GLP-1, each in lyophilized form.

Please include the following in your report:

  • Process flow diagram
  • Stream table data
  • Technical drawing and specification sheet of at least 3 selected unit operations
  • Design calculations to prove the purification will operate as intended
  • Other aspects selected based on their functioning in the unit
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