Isotonic oral solution

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RX 351 Lab – Module 8 Assignment (18pts)

Name _______________________________________________________________

Complete and submit on Canvas. You must show all work to receive full credit. Do not leave off units and make sure to use leading zeros. Dropping units in your answer or failure to use a leading zero in an answer will result in no credit for that answer, even if the number itself is correct.

(6pts) On a mission trip to Africa, you are asked to prepare 1L an isotonic oral solution to treat dehydration associated with diarrhea in the pediatric population of the area. The recipe is as follows:

Glucose 13.5g E-value=0.16

Potassium Chloride 1.5g E-value=0.78

NaCl qs to isotonic

Purified Water qs 1L

Calculate the amount of each ingredient then fill in the rest of the information for the recipe.

Storeroom Supplies: Glucose 20% Solution

Potassium Chloride 20% Solution

Normal Saline Solution

Purified Water

Completed Recipe:

Glucose 20% solution _______ml

Potassium Chloride 20% solution ________ml

Normal Saline solution _________ml (to provide _____g NaCl to make solution isotonic)

Purified Water qs 1000ml

(3pts) You have a summer research internship, and your preceptor asks you to prepare a barium solution for use in the lab. The recipe is as follows:

Barium 0.178% w/v solution 1ml

Purified Water qs 100ml

Calculate the concentration of barium in the mixture. Express in ppm (parts per million or ____g/1,000,000ml)

(4pts) A compounding pharmacist has a supply of 0.03% w/w tacrolimus ointment, used in the treatment of psoriasis. He receives a prescription for 180g of a 0.1% w/w tacrolimus ointment. With the goal of using the lower strength ointment before it expires, he plans to add tacrolimus powder to obtain the desired concentration of API. How should he prepare 180g of the ointment? Use the alligation method for this problem.

(5pts) During a short stay in the hospital, a patient received 24h of intravenous calcium to treat hypocalcemia. He has been receiving 100meq of elemental calcium IV daily. Now that he is going home, he is being switched to oral calcium. He is to continue an equivalent oral daily dose, divided 2-3 times a day. (AW of Ca=40)

Calculate a dosing regimen for the patient if he is purchasing the product pictured here. Round to nearest # of whole tablets.)

The patient’s serum calcium level is tested two weeks later. It is reported to you as 4meq/L. Your reference chart lists a normal calcium level as 8.5-10.5mg/dL. Convert the units to check to see if his calcium level is within range.